Research labs

Evolutionary Systems Biology lab

This lab’s main line of research at present focuses on the understanding of natural selection and adaptation in humans and primates through the comparative analysis of genomes. Its purpose is to understand complex adaptations through genome-wide analyses of the footprints that natural selection has left in genomes and attempt to place selection in a functional molecular framework of molecular pathways. The Evolutionary Systems Biology Lab is studying differential adaptation among human populations, including several African populations, Roma (as compared to Romanians and Indians) and in Chimpanzees. It has launched a project with the analysis of the haploid sequences of several individuals from all known groups of Southeast Asian pygmies.

Principal investigator: Jaume Bertranpetit

Members of the lab: Elizabeth Gabriela Aguileta Estrada, Postdoctoral Researcher; Begoña Dobon Berenguer, PhD Student; Hafid Laayouni El Alaoui, Postdoctoral Researcher; Jessica Marie Nye, PhD Student; Anastasios Soukoulis, Master Student; Pablo Villegas Mirón, PhD Student; Sandra Walsh Capdevila, PhD Student

Congresses organised: 1

Oral presentations and talks given: 10

Main publications and other research activities:

Paula Jofré, Payel Das, Jaume Bertranpetit and Robert Foley. Cosmic phylogeny: reconstructing the chemical history of the solar neighbourhood with an evolutionary tree. MNRAS (Monthly Notices of the Royal Astronomical Society) 467, 1140–1153 (2017) doi:10.1093/mnras/stx075

Mayukh Mondal, Anders Bergström, Yali Xue, FrancescCalafell, Hafid Laayouni, Ferran Casals, Partha P. Majumder, Chris Tyler-Smith* and Jaume Bertranpetit*. Y-Chromosomal sequences of diverse Indian populations and the ancestry of the AndamaneseHuman Genetics 2017 May;136(5):499-510

Sònia Casillas, Roger Mulet, Pablo Villegas-Mirón, Sergi Hervas, Esteve Sanz, Daniel Velasco, Jaume Bertranpetit, Hafid Laayouni and Antonio Barbadilla. PopHuman: the human population genomics browserNucleic Acids Research, 2017 Oct 20. doi: 10.1093/nar/gkx943

Maja P. Greminger, Alexander Nater, Tugce Bilgin Sonay, Marc Pybus, Marc de Manuel Montero, Tariq Desai, Guillem de Valles, Ferran Casals, Javier Prado-Martinez, Benoit Goossens, Ernst J. Verschoor, Kristin S. Warren, Ian Singleton, Laurentius N. Ambu, David Marques, Joko Pamungkas, Dyah Perwitasari-Farajallah, Puji Rianti, Ivo G. Gut, Marta Gut, Pablo Orozco-terWengel, Carel P. van Schaik, Jaume Bertranpetit, Maria Anisimova, Aylwyn Scally, Tomas Marques-Bonet, and Michael Krützen. Morphometric, behavioral, and genomic evidence for a new orangutan speciesCurrent Biology. 2017 S0960-9822(17)31245-9.

Ludovica Montanucci and Jaume Bertranpetit. Recombination. In N. Saitou (ed.) Evolution of the Human Genome I. Evolutionary Studies. Springer, Tokyo. pp. 131-142.

Main outreach activities:

Diàlegs Humanístics a la UPF: Dialogue between Jaume Bertranpetit and Victoria Reyes-Garcia, ICREA researcher at ICTA – UAB. “Biologia i cultura: determinisme i llibertat».

Programme Vicenç Vives, Esade. Open session with Pere Puigdomènech. Reptes de la Biotecnologia. CRAG, Bellaterra.

Conference in Camprodon: «La lluita contra l’envelliment i la mort»

Conference during the PRBB Open Day: “Una visió evolutiva entorn de l’envelliment i la mort”.

Organizer and moderator of a series of talks on “Genetics and language: what do we (not) know?” with the participation of Faraneh Vargha-Khadem, Dan Dediu and Anthony Monaco. Cosmocaixa, Barcelona.

Funding (active projects in 2017 only):

Name of the project Selección adaptativa en poblaciones humanes
Principal investigator Jaume Bertranpetit
Funding institution Ministerio de Economia, Industria y Competitividad


Name of the project Seqüenciació massiva d’ADN als estudis arqueològics
Principal investigator Jaume Bertranpetit
Funding institution Institut d’Estudis Catalans


Name of the project Consolidate Research Group 2017 SGR 702: «Human Population Genetics»
Principal investigator Jaume Bertranpetit
Funding institution Agència de Gestió d’Ajuts Universitaris i de Recerca (AGAUR)

More information:
Evolutionary Systems Biology lab’s website

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